Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1989-09-20
1997-06-17
Smith, Lynette F.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530350, 4242111, C07K 100, C07K 500, A61K 3800, A61K 39155
Patent
active
056398530
ABSTRACT:
Polypeptides, nucleotides, and compositions useful for preparing diagnostic reagents for and vaccines against human Respiratory Syncytial Virus are disclosed. The polypeptides include short polypeptides which are related to a neutralizing and fusion epitope of the Respiratory Syncytial Virus fusion protein or a neutralizing epitope of the G protein.
REFERENCES:
Walsh, et al., 1985, "Purification and Characterization of . . . " J. General Virology 66: 409-415.
Collins, et al. 1984, "Nucleotide Sequence of the Gene Encoding . . . " PNAS 81:7683-7687.
Elango et al., 1985, "Respiratory Syncylial Virus Fusion Glycoprotein . . . " Nucleic Acids Res. 13(5): 1559-74.
Satake, et al., 1985, "Respiratory Syncytial Virus Glycoprotein G . . . " Nucleic Acids Res. 13(21): 7795-7812.
Hopp et al., 1981 "Prediction of Protein Antigenic Determinants . . . " PNAS 78(6): 3824-3828.
Arumugham Rasappa
Hildreth Stephen W.
Hu Branda T.
Martin-Gallardo Antonia
Paradiso Peter R.
Baldwin Geraldine F.
Gordon Alan M.
Praxis Biologics, Inc.
Smith Lynette F.
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