Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-10-01
1976-04-20
Todd, G. Thomas
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260243B, 2602472B, 260268R, 26029381, 26029383, 26029384, 26032641, 2603265M, 260479R, 2605709, 424246, 424248, 424250, 424267, 424274, 424311, 424330, C07D29508
Patent
active
039519708
ABSTRACT:
Compounds of the formula ##SPC1##
And acid addition salts thereof, wherein R represents an alkyl group having 1 to 20 carbon atoms, an arylalkyl group, or a cycloalkyl-lower alkyl group, R.sub.1 and R.sub.2 represent hydrogen or the same or different lower alkyl or lower alkanoyl groups; and Z represents --NH.sub.2, --NHR.sub.3, --NR.sub.3 R.sub.4, or ##EQU1## WHERE R.sub.3 is lower alkyl, or phenyl-lower alkyl, R.sub.4 is lower alkyl or phenyl-lower alkyl, m is an integer from 0 to 6, n is an integer from 0 to 6, m + n is an integer from 3 to 6, and X is CH.sub.2, CHR.sub.3, O, S, or NR.sub.3.
The compounds have pharmacological activity, including antidepressant and anti-hypertensive activity, in animals.
REFERENCES:
patent: 3082113 (1963-03-01), Hemwall
Pars Harry George
Razdan Raj Kumar
Sharps Associates
Todd G. Thomas
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