Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1980-02-13
1982-03-30
Trousof, Natalie
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
26050117, 560 43, C07B 1900
Patent
active
043225489
ABSTRACT:
Process for the optical resolution of racemic mandelic acid which process comprises contacting said racemic mandelic acid with a phenylglycine ester or a phenylglycine ester hydrochloride in a reaction medium, and recovering the D(-)-mandelic acid and L(+)-mandelic acid form; certain D(-) and L(+)-phenylglycine esters and hydrochlorides are provided as novel resolution agents.
REFERENCES:
patent: 2820827 (1958-01-01), Ruschig et al.
patent: 3887606 (1975-06-01), Phillipps et al.
McKenzie, J. Chem. Soc., 75, p. 966, (1899).
Ingersoll et al., J. Amer. Chem Soc., 55, p. 411, (1933).
Roger, J. Chem. Soc., p. 1544, (1935).
Blaschke, Chem. Ber., 107, p. 237, (1974).
Kelly Kenneth W.
Kesslin George
Clarke Vera C.
Kay Fries, Inc.
Trousof Natalie
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