Resolution of immixtures of stereoisomeric alcohols

Details Resolution of immixtures of stereoisomeric alcohols Resolution of immixtures of stereoisomeric alcohols

1995-09-05

1998-02-03

Barts, Samuel

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568817, 568829, 568834, C07C 2974

Patent

active

057146420

ABSTRACT:
Immixture of stereoisomeric alcohols is resolved by selectively enzymatically acylating one of the stereoisomers thereof, in the presence of a catalytically effective amount of a hydrolase, for example a lipase, esterase or acylase, in a biphasic hydroorganic reaction medium, and thence separating the alcohol stereoisomer from the ester stereoisomer thus formed.

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