Resolution of a narwedine amide derivative

Details Resolution of a narwedine amide derivative Resolution of a narwedine amide derivative

2007-12-11

2007-12-11

Kifle, Bruck (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

10951748

ABSTRACT:
The present invention provides for an efficient method of effecting the resolution of a narwedine amide, and the synthesis of galantamine.

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D.H.R. Barton and G.W. Kirby,Pheonol Oxidation and Biosynthesis Part V, The Synthesis of Galanthamine, J.Chem. Soc., p. 806 (1962).
T. Kametani et al.,Studies on the Syntheses of Heterocyclic Compounds, Part CCCLXXXVI, Alternative Total Syntheses of Galanthamine and N-Benzylgalanthamine Iodide, J. Chem. Soc., p. 2602 (1969).

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