Resolution of (+)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]ind

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D491052

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045018995

ABSTRACT:
Racemic (+)-1,8-diethyl-1,3,4,9-tetrahydroprano[3,4-b]indole-1-acetic acid is resolved with cholesteryl aniline to obtain directly the pure salt of the (+)-enantiomer with cholesteryl aniline and converting the latter salt to the pure (+)-enantiomer.

REFERENCES:
patent: 3939178 (1976-02-01), Demerson et al.
Julian et al., J. Am. Chem. Soc. 70 1834-1837 (1948).
Sandor Muller et al., Chem. Abst., vol. 35, 6243.
Erzsebet Batyka, Chem. Abst., vol. 36, 484.
Demerson et al., J. Med. Chem., 18, 189 (1975).

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