Resolution

Details Resolution Resolution

1997-02-07

1999-04-06

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

558406, C07C25503

Patent

active

058920935

ABSTRACT:
A reproducible process for preparing a substantially single enantiomer (R or S) of 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexanoic acid, or an analogue thereof, thereby providing single enantiomer acid for the first time, proceeds by means of a classical salt resolution employing a resolving agent selected from an enantiomer (R or S) of a 1-arylalkylamine and (-)-quinine, and provides novel salts that are readily convertible to verapamil.

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