Resistance sequences and uses thereof

Details Resistance sequences and uses thereof Resistance sequences and uses thereof

2005-08-23

2005-08-23

Canella, Karen A. (Department: 1642)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S006120, C435S007100, C436S501000, C436S503000, C436S504000

Reexamination Certificate

active

06933105

ABSTRACT:
Increased expression of resistance sequences is associated with drug resistance of certain cells (e.g., cancer cells). The invention provides methods for identifying drug resistant cells by measuring the expression or activity of resistance genes (e.g., semaphorin D, B94, mel-14 antigen, 24p3, proliferin, or maspin), methods for identifying modulators of drug resistance, and methods for modulating drug resistance by modulating the expression or activity of resistance sequences.

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