Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1991-03-19
1994-03-15
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435222, 43525231, 4352525, 435839, 4353201, 536 232, 935 38, 935 44, C12P 2106
Patent
active
052945421
ABSTRACT:
A Bacillus cell containing a mutation in the residual protease III (rp-III) gene resulting in the inhibition of the production by the cell of proteolytically active RP-III.
REFERENCES:
patent: 4828994 (1990-05-01), Fahnestock et al.
patent: 4946789 (1990-08-01), Udaka et al.
Kawamura et al., "Construction of a Bacillus subtilis Double Mutant Deficient in Extracellular Alkaline and Neutral Proteases," J. of Bacteriology 160(1):442-444 (1984).
Koide et al., "Cloning and Sequencing of the Major Intracellular Serine Protease Gene of Bacillus subtilis," J. of Bacteriology 167(1):110-116 (1986).
Stahl et al., "Replacement of the Bacillus subtilis Subtilisin Structural Gene with an In Vitro-Derived Deletion Mutation," J. of Bacteriology 158(2):411-418 (1984).
Yang et al., "Cloning of the Neutral Protease Gene of Bacillus subtilis and the Use of the Cloned Gene to Create an In Vitro-Derived Deletion Mutation," J. of Bacteriology 160(1):15-21 (1984).
Pero Janice
Rufo, Jr. Gerald A.
Sloma Alan
Omnigene, Inc.
Schmickel D.
Wax Robert A.
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