Reproducible objective quantification method to segment...

Image analysis – Applications – Biomedical applications

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C382S173000

Reexamination Certificate

active

08077937

ABSTRACT:
The invention provides a reproducible, objective quantification technique that reliably segments white matter structures. The technique receives a seed voxel within the white matter structure from an individual, determines thresholds and selection criteria, creates a binary mask based on the at least one threshold and the at least one selection criteria and calculates the boundary of the white matter structure based on the binary mask. A magnification factor is applied to each component of the eigenvectors of voxels. Boundary voxels are determined wherein each of the boundary voxels has a magnitude above a predetermined value and is located next to a voxel having a magnitude below the predetermined value. A vector is drawn from the seed voxel to a boundary voxel and the boundary voxels are connected together, thereby forming the region of interest within the connected boundary voxels.

REFERENCES:
patent: 5841892 (1998-11-01), McGrath et al.
patent: 6366797 (2002-04-01), Fisher et al.
patent: 6614226 (2003-09-01), Wedeen
patent: 6731782 (2004-05-01), Ashton
patent: 7020314 (2006-03-01), Suri et al.
patent: 7024027 (2006-04-01), Suri et al.
patent: 2003/0053697 (2003-03-01), Aylward et al.
patent: 2004/0101179 (2004-05-01), Suryanarayanan et al.
Watts et al., Fiber Tracking using Magnetic Resonance Diffusion Tensor Imaging and its Applications to Human Brain Development, Dept. of Radiology, Psychiatry, and Neuroscience, Weill Medical College of Cornell Univ., pp. 1-30.
Butler Hospital Memory & Aging Program; Researchers at Butler Hospital Memory & Aging using diffusion-tensor imaging (DTI) to study white matter in the brain; Website; Date Last Visited Jun. 10, 2005; 4 pages; http://www.memorydisorder.org/research/dtimri—imaging/dti.htm.
PUBMED; Automatic detection of white matter lesions in magnetic resonance brain images; Website; Date Last Visited Jul. 11, 2005; 1 page; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list—uids=2401131&dopt=....
Leiden University Medical Center; Neuro-Image Processing Sectin, Brain-O-Matic, A Software for White Matter Lesion Detection in Dual Images (T2 and PD), Faiza Admiraal-Behloul, Jorrit Schaap (MRI Section); Website; Date Last Visited Jul. 11, 2005; 5 pages; http://www.lumc.nl/1010/LKEBHome/english/research/Neuro/BrainOMatic/LKEB—NIP—Brainomatic.html.
Fractional Segmentation of White Matter; Simon K. Warfield, Carl-Fredrik Westin, Charles R. G. Guttman, Marilyn Albert, Ferenc A. Jolesz, Ron Kikinis; Website; Date Last Visited Jun. 27, 2005; 11 pages; http://splweb.bwh.harvard.edu:8000/pages/papers/warfield/miccai99/.
Mariana Lazar, David M. Weinstein, Jay S. Tsuruda, Khader M. Hasan, Konstantinos Arfanakis,M. Elizabeth Meyerand, Benham Badie, Howard A. Rowley, Victor Haughton, Aaron Field, and Andrew L. Alexander; White Matter Tractography Using Diffusion Tensor Deflection; Human Brain Mapping 18:306-321 (2003) © 2003 Wiley-Liss, Inc.; 16 pages.
Faguo Yang, Tianzi Jiang, Wanlin Zhu, and Frithjof Kruggel; White Matter Lesion Segmentation from Volumetric MR Images; International Workshop in Medical Imaging and Augmented Reaility; Aug. 19-20, 2004; 8 pages.
Pierre Fillard, John Gilmore, Joseph Piven, Weili Lin, Guido Gerig; Quantitative Analysis of White Matter Fiber Properties along Geodesic Paths; Report; In Medical Image Computing and Computer-Assisted Intervention 2003 proceedings LNCS 2879: 16-23; Nov. 15-18, 2003; 9 pages.
Edward A. Ashton, PhD, Chihiro Takahashi, MD, Michel J. Berg, MD, Andrew Goodman, MD, Saara Totterman, MD, PhD, Sven Ekholm, MD, PhD; Accuracy and reproducibility of manual and semi-automated quantification of MS lesions in MRI; Running Title: Reproducibility of MS lesion measurement; Proceedings of SPIE MI 2002; Feb. 23, 2002; 18 pages.
Xingchang Wei, MD, Simon K. Warfield, PhD, Kelly H. Zou, PhD, Ying Wu, MD, Xiaoming Li, MD, Alexandre Guimond, PhD, John P. Mugler III, PhD, Randall R. Benson, MD, Leslie Wolfson, MD, Howard L. Weiner, MD, and Charles R. G. Guttmann, MD; Quantitative Analysis of MRI signal Abnormalities of Brain White Matter With High Reproducibility and Accuracy; Journal of Magnetic Resonance Imaging 15:203-209 (2002), DOI 10.1002/jmri.10053; © 2002 Wiley-Liss, Inc.; 7 pages.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Reproducible objective quantification method to segment... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reproducible objective quantification method to segment..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reproducible objective quantification method to segment... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4266617

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.