Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1992-07-02
1994-10-18
Yarbrough, Amelia Burgess
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 9121, 435 9131, 536 231, 536 2431, 536 2432, 935 77, 935 78, C12Q 168
Patent
active
053567749
ABSTRACT:
This invention relates to the use of functional reporter molecules in the detection and measurement of nucleic acid sequences in a sample, as a determination, for example, of pathogenic disease existence or potential. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target nucleic acid sequence.
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Axelrod Vladimir D.
Kramer Fred R.
Lizardi Paul M.
Mills Donald R.
Burgess Yarbrough Amelia
The Trustees of Columbia University in the City of New York
White John P.
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