Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-10-17
1997-04-15
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 4, 435 71, 435 15, 435 14, 435 9121, 4351723, 4353201, 536 221, 536 241, 935 77, 935 78, C07H 2104, C07H 2100, C12P 1934, C12Q 168
Patent
active
056208510
ABSTRACT:
This invention relates to the use of functional reporter molecules in the detection and measurement of targets in a sample. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target.
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Axelrod Vladimir D.
Kramer Fred R.
Lizardi Paul M.
Mills Donald R.
Jones W. Gary
The Trustees of Columbia University in the City of New York
Tran Paul B.
White John P.
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