Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.
Patent
1984-05-08
1987-05-26
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Tripeptides, e.g., tripeptide thyroliberin , etc.
530330, 530329, C07K 508, C07K 510, C07K 706
Patent
active
046687700
ABSTRACT:
Renin inhibitory peptides of the formula ##STR1## and analogs thereof inhibit renin and are useful for treating various forms of renin-associated hypertension and hyperaldosteronism.
REFERENCES:
Boger et al., Nature, 303, 81-84 (1983).
Parsons, Peptide Hormones, (Jun. 1976) University Park Press, Baltimore, pp. 1-7.
Boger Joshua S.
Evans Ben E.
Veber Daniel F.
Elder Richard A.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Phillips Delbert R.
Speer Raymond M.
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