Renin inhibitory peptides containing an N-alkyl-histidine moiety

Details Renin inhibitory peptides containing an N-alkyl-histidine moiety Renin inhibitory peptides containing an N-alkyl-histidine moiety

1988-01-20

1989-11-14

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 514400, 530330, 530331, 530328, 548344, A61K 3743, C07K 706, C07K 508, C07K 510, C07K 506

Patent

active

048807818

ABSTRACT:
The present invention provides novel renin-inhibiting peptides and novel processes and intermediates for the preparation of both novel and known renin-inhibiting peptide analogs. Such inhibitors are useful for the diagnosis and control of renin-dependent hypertension.

REFERENCES:
patent: 4242256 (1980-12-01), Sharpe et al.
patent: 4297346 (1981-10-01), Rips et al.
patent: 4424207 (1984-01-01), Szelke et al.
patent: 4470971 (1984-09-01), Boger et al.
patent: 4477440 (1984-10-01), Boger et al.
patent: 4477441 (1984-10-01), Boger et al.
patent: 4478826 (1984-10-01), Veber et al.
patent: 4478827 (1984-10-01), Haber et al.
patent: 4479941 (1984-10-01), Verber et al.
patent: 4485099 (1984-11-01), Boger et al.
patent: 4511504 (1985-04-01), McCullagh et al.
Derwent Abstr. 156322, 3/27/84.
Derwent Abstr. 172346, 3/22/84.
Derwent Abstr. 163237, 5/29/84.
Derwent Abstr. 156321, 3/27/84.
Derwent Abstr. 172347, 6/22/84.
Derwent Abstr. WO/8403044, 2/7/83.
Synthetic Peptides, vol. 6 (1984), 224, 225, 240, 241, 266.
Holladay et al., "Synthesis of Hydroxyethylene and Ketomethylene Dipeptide Isosteres", vol. 24, No. 41, pp. 4401-4404, 1983.

Affiliated with

Also associated with

Rating

Renin inhibitory peptides containing an N-alkyl-histidine moiety does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Renin inhibitory peptides containing an N-alkyl-histidine moiety, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Renin inhibitory peptides containing an N-alkyl-histidine moiety will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1852917