Renin inhibitory peptides

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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2601125R, C07C10352, A61K 3702

Patent

active

044788266

ABSTRACT:
Renin inhibitory peptides of the formula ##STR1## and analogs thereof inhibit renin and are useful for treating various forms of renin-associated hypertension and hyperaldosteronism.

REFERENCES:
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patent: 4185096 (1980-01-01), Castero et al.
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patent: 4384994 (1983-05-01), Veber et al.
Kund et al., Biochem. Biophys. Acta, 452(2), 533-537 (1976).
Powers et al., Acid Proteases, Structure, Function and Biology, Plenum Press 1977, 141-157.
Trends in Biochem. Sci., 1, 205-208(1976).

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