Renin-inhibitory di-, tri-, and tetrapeptides

Details Renin-inhibitory di-, tri-, and tetrapeptides Renin-inhibitory di-, tri-, and tetrapeptides

1989-03-03

1991-09-17

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 530330, 530331, 546133, A61K 3702, C07K 506, C07K 508, C07K 510

Patent

active

050495488

ABSTRACT:
Renin-inhibitory di-, tri-, and tetrapeptides of the formula I:

REFERENCES:
patent: 4748155 (1988-05-01), Sisto et al.
patent: 4812442 (1989-03-01), Boger et al.
Chorev et al., "Partially Modified Retro-Inverso Peptide Analogs", Chem. Abstracts, vol. 105, 108710g, 1986.
Burger, Medicinal Chemistry, 2nd Ed., 1960, pp. 565-571, 579-581, 600-601.
Denkewalter et al., Progress In Drug Research, vol. 10, 1966, pp. 610-612.
Plattner et al., J. Med. Chem., 1988, 31(12): 2277-2288.
Bolis et al., J. Med. Chem., 1987, 30(10): 1729-1737.
Haber, et al., J. Cardiovasc. Pharmacol., 1987, 10(Suppl. 7): 554-558.

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