Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-02-04
1989-09-05
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 19, 530331, A61K 3743, C07K 506, C07K 508
Patent
active
048639052
ABSTRACT:
The invention concerns novel renin-inhibiting peptides which are modified as isosteres. These peptides are useful for treating renin-associated hypertension and hyperaldosteronism. Processes for preparing the peptides, compositions containing them and methods for using them are included. Also included is a diagnostic test using the peptides to determine the presence of renin-associated hypertension or hyperaldosteronism.
REFERENCES:
patent: 4479941 (1986-05-01), Veber et al.
patent: 4609643 (1986-09-01), Szelke et al.
patent: 4661473 (1987-04-01), Boger et al.
patent: 4663310 (1987-05-01), Beck et al.
patent: 4668663 (1987-05-01), Boger et al.
patent: 4668770 (1987-05-01), Boger et al.
Hudspeth James P.
Kaltenbronn James S.
Repine Joseph T.
Woo Peter W. K.
Anderson Elizabeth M.
Phillips Delbert R.
Warner-Lambert & Company
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