Renin inhibitors having all retro-inverted peptide bonds

Details Renin inhibitors having all retro-inverted peptide bonds Renin inhibitors having all retro-inverted peptide bonds

1990-07-13

1992-03-10

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 530323, 530331, 530332, 548344, 562445, A61K 31195, A61K 3702, C07K 502, C07K 506

Patent

active

050950061

ABSTRACT:
Renin-inhibiting peptides of the formula ##STR1## in which X represents a group of the formula ##STR2## represents hydroxyl, alkoxy having up to 8 carbon atoms, benzyloxy or a group of the formula --NR.sup.4 R.sup.5,

REFERENCES:
patent: 4560505 (1985-12-01), Pinori et al.
patent: 4585586 (1986-04-01), Di Trapani et al.
S. H. Rosenberg et al., J. Medicinal Chemistry 30:1224-1228, 1987.
Bolis et al., J. Med. Chem. 30: 1729-1739, 1987.
Haber et al., J. Cardiovasc. Pharmac. 10(Supp. 7): S54-S58, 1987.
Plattner et al., J. Med. Chem. 31:2277-2288, 1988.
Denkewalter et al., Prog. in Drug Research 10:511-512, 1966.
A. Burger, editor, Medicinal Chemistry, 2nd Edition, pp. 565-571, 578-581, 600-601, 1960.

Affiliated with

Also associated with

Rating

Renin inhibitors having all retro-inverted peptide bonds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Renin inhibitors having all retro-inverted peptide bonds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Renin inhibitors having all retro-inverted peptide bonds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2284620