Renin inhibitors and aminoacid and aminoaldehyde derivatives

Details Renin inhibitors and aminoacid and aminoaldehyde derivatives Renin inhibitors and aminoacid and aminoaldehyde derivatives

1987-03-06

1989-04-04

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 514 18, 514 19, 530328, 530329, 530330, 530331, A61K 3702, C07K 706, C07K 508, C07K 510

Patent

active

048187488

ABSTRACT:
Anti-hypertensive compounds of the formula ##STR1## in which A represents hydrogen, C.sub.1 -C.sub.8 -alkyl, C.sub.7 -C.sub.14 -aralkyl, phenylsulphonyl, tolylsulphonyl or C.sub.1 -C.sub.8 -alkylsulfphonyl, or represents an aminoprotective group,

REFERENCES:
patent: 4661473 (1987-04-01), Boger et al.
patent: 4668663 (1987-05-01), Boger
patent: 4668770 (1987-05-01), Boger et al.
Matsueda et al., Chemistry Letters, pp. 1041-1044, 1985.
M. Szelke, B. Leckie, A. Hallet, D. M. Jones, J. Sueiras, B. Atrash, Y. A. F. Lever, Potent New Inhibitors Human Renin, Nature, vol. 299, pp. 555-557, Oct. 7, 1982.

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