Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Silicon containing doai
Patent
1988-11-03
1992-12-08
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Silicon containing doai
514 64, 514 2, 549 4, 549213, 518110, 518405, 564 8, 558288, 558289, 546 13, 562 7, A61K 3169, A61K 31698, C07D33358
Patent
active
051698412
ABSTRACT:
The invention relates to compounds of the formula 1 ##STR1## in which A.sup.1 denotes a radical of the formulae ##STR2## A.sup.2 is absent or represents a radical of the formula ##STR3## R.sup.2, R.sup.3 and R.sup.4 are as defined in the specification, and X and Y, independently of one another, represent --O-- or --NR.sup.13 --, and to the salts thereof. Also described is a process for the preparation of the compounds of the formula 1, corresponding pharmaceutical products, and the use thereof as medicines, and intermediates for the preparation of these compounds.
REFERENCES:
patent: 4499082 (1985-02-01), Shenvi et al.
Smith, et al., "Principles of Biochemistry: Mammalian Biochemistry," 7th ed., pp. 158-163, McGraw-Hill Book Co., New York (1983).
Hui et al., J. Med. Chem., vol. 30, pp. 1287-1295 (1987).
J. Med. Chem., 1985, vol. 28, pp. 1917-1925, American Chem. Soc., D. H. Kinder et al., "Acylamino Boronic Acids and Difluoroborane . . .".
Kleeman Heinz-Werner
Ruppert Dieter
Scholkens Bernward
Urbach Hansjorg
Hoechst Aktiengesellschaft
Raymond Richard L.
Russell Mark W.
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