Renin inhibitors

Details Renin inhibitors Renin inhibitors

1991-10-02

1993-09-07

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 530323, 530330, 530331, 5483147, 5483381, 5483121, 5483151, 5483124, 562445, A61K 31195, A61K 3702, C07K 502, C07K 506

Patent

active

052429032

ABSTRACT:
Renin-inhibiting peptides of the formula ##STR1## in which X represents a group of the formula ##STR2## represents hydroxyl, alkoxy having up to 8 carbon atoms, benzyloxy or a group of the formula --NR.sup.4 R.sup.5,

REFERENCES:
patent: 4560505 (1985-12-01), Pinuri et al.
patent: 4585586 (1986-04-01), Ditrapani et al.
Johnson, Rodney L., J. Med. Chem., (1983), 26, pp. 1457-1462.
Johnson, Rodney L. and Verschoor, Karen, J. Med. Chem., (1980), 23, pp. 666-669.
Bolis et al., J. Med. Chem., 30: pp. 1729-1737 (1987).
Haber et al. J. Cardiovasc. Pharmac. 10 (Supp. 7) pp. 554-558.
Plattner et al., J. Med. Chem. 31: 2277-2288, (1988).
Denkewalter et al., Progress in Drug Research, 10: 511-512 (1966).
A. Burger, editor., Medicinal Chemistry, 2nd edition, pp. 565-571, 578-581, 600-601 (1960).

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