Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-11-28
1992-05-19
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142315, 5142388, 544147, 544159, 544160, 544162, 544165, 544168, A61K 31395, C07D26530
Patent
active
051149370
ABSTRACT:
The invention concerns novel renin-inhibitory compounds which are useful for treating renin-associated hypertension, congestive heart failure, hyperaldosteronism, glaucoma, and diseases caused by retroviruses including HTLV-I, -II, and -III. Processes for preparing the compounds, novel intermediates useful in the preparation thereof, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, congestive heart failure, or hyperaldosteronism.
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Stein and Marcotte, MEDI, Abst. 85, 194th ACS Meeting, New Orleans, Aug. 1987.
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Hamby James M.
Kaltenbronn James S.
Repine Joseph T.
Anderson Elizabeth M.
Richter Johann
Warner-Lambert & Company
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