Renal regulatory elements and methods of use thereof

Details Renal regulatory elements and methods of use thereof Renal regulatory elements and methods of use thereof

2007-02-20

2007-02-20

Qian, Celine (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S325000, C435S069100

Reexamination Certificate

active

10311388

ABSTRACT:
Disclosed are cis-acting regulatory elements from a KIM-1 gene. The elements can be used to direct the expression of operably linked sequences in renal tissue.

REFERENCES:
patent: 5622861 (1997-04-01), Kaplan et al.
patent: 6664385 (2003-12-01), Sanicola-Nadel et al.
patent: 2003/0124114 (2003-07-01), McIntire et al.
patent: 2003/0215831 (2003-11-01), Sanicola-Nadel et al.
patent: 2004/0005322 (2004-01-01), Kuchroo et al.
patent: 2004/0180038 (2004-09-01), Hancock et al.
patent: 2005/0095593 (2005-05-01), McIntire et al.
patent: 2005/0112117 (2005-05-01), Bailly et al.
patent: WO 96/04376 (1996-02-01), None
patent: WO 97/44459 (1997-11-01), None
patent: WO 97/44460 (1997-11-01), None
patent: WO 98/20110 (1998-05-01), None
patent: WO 01/98481 (2001-12-01), None
patent: WO 03/025138 (2003-03-01), None
patent: WO 03/042661 (2003-05-01), None
patent: WO 03/080856 (2003-10-01), None
patent: WO 04/005544 (2004-01-01), None
patent: WO 04/084823 (2004-10-01), None
patent: WO 05/001092 (2005-01-01), None
Database No. AC005603, Homo sapiens subtelomeric cosmid 11b-1, Sep. 3, 1998.
Adams et al. Use of a random human BAC end sequence database for sequence ready map building. Gene Bank accession No. AQ277590. Nov. 22, 1998.
Bailly, V., et al., “Shedding of Kidney Injury Molecule-1, a Putative Adhesion Protein Involved in Renal Regeneration,” Journal of Biological Chemistry, (2002) 277(42):39739-39748.
Berg et al., “L-selectin-mediated Lymphocyte Rolling on MadCAM-1,” Nature (1993) 366:695-698.
Berlin et al., “alpha-4-beta-7 Integrin Mediates Lymphocyte Binding to the Mucosal Vascular Address in MAdCAM-1,” Cell (1993) 74:185-195.
Bonventre and Colvin, “Adhesion Molecules in Renal Disease,” Current Opinion in Nephrology and Hypertension (1996) 5:254-261.
Briskin et al., “MAdCAM-1 has Homology to Immunoglobulin and Mucin-like Adhesion Receptors and to IgA1,” Nature (1993) 363:461-464.
Dudley et al., “A Requirement for Bone Morphogenetic Protein-7 During Development of the Mammalian Kidney and Eye,” Genes & Development (1995) 9:2795-2807.
Fagotto and Gumbiner, “Cell Contact-Dependent Signaling,” Developmental Biology (1996) 180:445-454.
Feigelstock et al., “The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor,” J. Virol. (1998) 72:6621-6628.
Greve et al., “The Major Hyman Rhinovirus Receptor Is ICAM-1,” Cell (1989) 56:839-847.
Hubank and Schatz. “Identifying Differences in mRNA Expression by Representational Difference Analysis of cDNA,” Nucleic Acids Research (1994) 22:5640-5648.
Kaplan et al. “Identification of a Surface Glycoprotein on African Green Monkey Kidney Cells as a Receptor for Hepatitis A Virus,” EMBO (1996) 15:4282-96.
Klinken et al, “Mucin Gene Structure and Expression: Protection vs. Adhesion,” Am J. Physiol. (1995) 269:G613-G627.
Kuchroo, et al. “TheTimGene Family: Emerging Roles in Immunity and Disease,” Nat. Rev. Immunol. (2003) 3:454-62.
Lin G. et al., “Expression of CD34 in endothelial cells, hematopoietic progenitors and nervous cells in fetal and adult mouse tissues, ”Eur. J. Immunol. (1995) 25:1508-1516.
Luo et al., “BMP-7 is an Inducer of Nephrogensis and is also Required for Eye Development and Skeletal Patterning,” Genes & Development (1995) 9:2808-2820.
McIntire et al. “Indentification ofTapr(An Airway Hyperreactivity Regulator Locus) and the LinkedTimGene Family,” Nat. Immunol. (2001):2:1109-16.
Monney et al., “Th1-Specific Cell Surfaces Protein Tim-3 Regulates Macrophage Activation and Severity of an Autoimmune Disease,” Nature (2002) 415:536-41.
Muller et al., “Integrin alpha8-beta1 is Critically Important for Epithelial-Mesenchymal Interactions During Kidney Morphogenesis” Cell (1997) 88:603-613.
Owens et al., “The genetic engineering of monoclonal antibodies,” J. Immunol. Methods. (1994) 168:149-165.
Rieger et al., Glossary of Genetics. 5th Edition, Springer-Verlag, NY, (1991) 16-17.
Rudikoff et al., “Single amino acid substitution altering antigen-bidning specificity,” Proc. Nat. Acad. Sci., USA, (1982) 79:1979-1983.
Sastry and Horwitz, “Adhesion-Growth Factor Interactions During Differentiation: An Integrated Biological Response,” Developmental Biology (1996) 180:455-467.
Shimizu et al., “Mucins in the Mainstream,” Nature (1993) 336:630-631.
Shyjan et al., “Human Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1) Demonstrates Structural and Functional Similarities to the alpha-4-beta-7-Integrin Binding Domains of Murine MAdCAM-1,” J. of Immunology (1996) 156:2851-2857.
Skolnick et al., “From genes to protein structure and function: novel applications of computational approaches in the genomic era,” Tibtech (2000) 18:34-39.
Takada et al., “The Cytokine-adhesion Molecule Cascade in Ischemia/Reperfusion Injury of the Rat Kidney,” J. Clin. Invest. (1997) 99:2682-2690.
Thadhani et al., “Acute Renal Failure,” NEJM (1996) 334:1448-1460.
Thompson et al., “The Cys-Rich Region of Hepatitis A Virus Cellular Receptor 1 is Required for Binding of Hepatitis A Virus and Protective Monoclonal Antibody 190/4, ”J. of Virology (1998) 72(5):3751-3761.
Weterman et al., “nmb, A Novel Gene, is Expressed in Low-Metastic Human Melanoma Cell Lines and Xenografts,” Int. J. Cancer (1995) 60:73-81.
Database Accession No. AC026777 (XP-002207936), “Homo sapiens chromosome 5 clone CTC-332D4, complete sequence”, retrieved from EMBL, Mar. 27, 2000.
Database Acession No. AQ277590 (XP-002207937), “CITBI-E1—2517G14.TF CITBI-E1 Homo sapiens genomic clone 2517G14, genomic survey sequence”, retrieved from EMBL, Nov. 23, 1998.
Database Accession No. AL022721 (XP-002207938), “Human DNA Sequence from clone 109F14 on chromosome 6p21.2-21.3”, retrieved from EMBL, Apr. 27, 1998.
Faure et al., “Differentially Expressed Genes in Ischemic Acute Renal Failure”, Mol. Biol. of the Cell, Bethesda, MD, 1998, 9:473A (XP-000953127).
Ichimura et al., “Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule . . . ”, J. Biol. Chem. 273(7):4135-4142, 1998 (XP-002079926).
Padanilam et al., “Molecular mechanisms of cell death and regeneration in acute ischemic renal injury”, Current Opinion in Nephrology and Hypertension, Rapid Science, London, GB, 1999, 8(1):15-19.
Rosenberg et al., “Differential gene expression in the recovery from ischemic renal injury”, Kidney International 39:1156-1161, 1991 (XP-000953186).

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