Renal function improvement

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07868042

ABSTRACT:
This invention relates to a method of improving renal function comprising administering to a subject in need thereof a composition comprising the inventive compounds. Also disclosed is a method of improving renal function where the subject is at risk of or suffering from renal failure.

REFERENCES:
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patent: 4026624 (1992-01-01), None
patent: 5043459 (1993-02-01), None
patent: 5279164 (1993-10-01), None
Yokozawa T. et al.Proof that green tea tannin suppresses the increase in the blood methylguanidine level associated with renal failure. Experimental and toxicologic pathology :49(1-2) (Feb. 1997).
Yokozawa T. et al.Effects of rhubarb tannins on renal function in rats with renal failure. Nippon Jinzo Gakkai shi 35(1) (Jan. 1993).
Yokozawa T. et al.Effects of rhubarb tannins on uremic toxins. Nephron 58 (2) (1991).
Hannemann J. et al.Cisplatin-induced lipid peroxidation and decrease of gluconeogenesis in rat kidney cortex: different effects of antioxidants and radical scavengers. Toxicology 51 (2-3) (Oct. 1988).
Sepulveda F. et al.Effect of(+)-catechin on renal and intestinal transport. Experientia 32(1) (1976).
Baumann J. et al.A structure-activity study on the influence of phenolic compounds and bioflavonoids on rat renal prostaglandin synthetase. Naunyn-Schmiedeberg's Archives of Pharmacology 307(1) (1979).

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