Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1988-06-08
1991-01-08
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530416, 530417, 530412, 530413, C07K 322, C07K 318
Patent
active
049837222
ABSTRACT:
Protein A is selectively isolated from an antibody--Protein A mixture by exposing the mixture to an anion exchange material under conditions sufficient to adsorb both components and then sequentially eluting the antibodies and protein A under conditions of increasing ionic strength. Resulting antibody preparations have less than about 15 ng of Protein A per mg of antibody.
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Bloom James W.
Mitra Gautam
Wong Melvin F.
Bradley Bertram
Furman Keith C.
Giblin James A.
Miles Inc.
Moskowitz Margaret
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