Removal of heparin from heparin-containing blood plasma samples

Details Removal of heparin from heparin-containing blood plasma samples Removal of heparin from heparin-containing blood plasma samples

1978-08-04

1980-04-15

Garvin, Patrick

Compositions

Preservative agents

Anti-oxidants or chemical change inhibitants

252426, 252477R, 210 40, B01D 1504

Patent

active

041983149

ABSTRACT:
This invention relates to a tableted form of fibrous triethylaminoethyl cellulose suitable for the removal of heparin from heparin-containing blood plasma. The tablet is composed of granular microcrystalline cellulose and fibrous triethylaminoethyl cellulose in a ratio of from about 5.4:1 to about 10:1. According to the method of this invention, the triethylaminoethyl cellulose tablet, which is formulated to provide from about 5 to about 26 mg. of triethylaminoethyl cellulose per milliliter of plasma sample, is added to a heparin-containing blood plasma sample, the sample is agitated or allowed to stand for a time sufficient to permit adsorption of substantially all heparin present. The sample is then centrifuged and the remaining heparin-free plasma can be subjected to coagulation testing in order to determine the true clotting time.

REFERENCES:
patent: 2128432 (1938-08-01), Ramage
patent: 2687990 (1954-08-01), Weisz
patent: 4055510 (1977-10-01), Peska et al.
Nealon et al., "An Extracorporeal Device to Treat Barbiturate Poisoning," JAMA, Jul. 11, 1966, vol. 197, No. 2, pp. 158-160.
Thompson et al., "Removal of Heparin and Protamine from Plasma," J. Lab. Clin. Med. 88, pp. 922-929, Dec. 1976.

Affiliated with

Also associated with

Rating

Removal of heparin from heparin-containing blood plasma samples does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Removal of heparin from heparin-containing blood plasma samples , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Removal of heparin from heparin-containing blood plasma samples will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-475384