Remote reagent chemical ionization source

Details Remote reagent chemical ionization source Remote reagent chemical ionization source

2007-08-07

2007-08-07

Berman, Jack I. (Department: 2881)

Radiant energy

Ionic separation or analysis

With sample supply means

C250S282000, C250S286000

Reexamination Certificate

active

11491634

ABSTRACT:
An improved ion source for collecting and focusing dispersed gas-phase ions from a reagent source at sub-atmospheric or intermediate pressure, having a remote source of reagent ions separated from a low-field sample ionization region by a barrier, comprised of alternating laminates of metal and insulator, populated with a plurality of openings, wherein DC potentials are applied to each metal laminate necessary for transferring reagent ions from the remote source into the low-field sample ionization region where the reagent ions react with neutral and/or ionic sample forming ionic species. The resulting ionic species are then introduced into the vacuum system of a mass spectrometer or ion mobility spectrometer. Embodiments of this invention are methods and devices for improving sensitivity of mass spectrometry when gas and liquid chromatographic separation techniques are coupled to sub-atmospheric and intermediate pressure photo-ionization, chemical ionization, and thermal-pneumatic ionization sources.

REFERENCES:
patent: 5961772 (1999-10-01), Selwyn
patent: 6228330 (2001-05-01), Herrmann et al.
Cody,R.B., et al., “Versatile new ion source for the analysis of materials in open air under ambient conditions”, Anal Chem 77, pp. 2297-2302 (2005).
McEwen, C.N., et al., “Analysis of solids, liquids, and biological tissues using solids probe introduction at atmostpheric pressure . . . ”, Anal Chem 77, pp. 7826-7831 (2005)..

Affiliated with

Also associated with

Rating

Remote reagent chemical ionization source does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Remote reagent chemical ionization source, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Remote reagent chemical ionization source will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3884605