Remote reagent chemical ionization source

Details Remote reagent chemical ionization source Remote reagent chemical ionization source

2006-08-22

2006-08-22

Wells, Nikita (Department: 2881)

Radiant energy

Ionic separation or analysis

With sample supply means

C250S281000, C250S286000

Reexamination Certificate

active

07095019

ABSTRACT:
An improved ion source and portable analyzer for collecting and focusing dispersed gas-phase ions from a reagent source at atmospheric or intermediate pressure, having a remote source of reagent ions generated by direct or alternating currents, separated from a low-field sample ionization region by a stratified array of elements, each element populated with a plurality of openings, wherein DC potentials are applied to each element necessary for transferring reagent ions from the remote source into the low-field sample ionization region where the reagent ions react with neutral and/or ionic sample forming ionic species. The resulting ionic species are then introduced into the vacuum system of a mass spectrometer or ion mobility spectrometer. Embodiments of this invention are methods and devices for improving sensitivity of mass spectrometry when gas and liquid chromatographic separation techniques or probes containing samples are coupled to atmospheric and intermediate pressure photo-ionization, chemical ionization, and thermospray ionization sources.

REFERENCES:
patent: 4209696 (1980-06-01), Fite
patent: 4531056 (1985-07-01), Labowsky et al.
patent: 4542293 (1985-09-01), Fenn et al.
patent: 4546253 (1985-10-01), Tsuchiya et al.
patent: 4999492 (1991-03-01), Nakagawa
patent: 5192865 (1993-03-01), Zhu
patent: 5412208 (1995-05-01), Covey et al.
patent: 5436446 (1995-07-01), Jarrell et al.
patent: 5559326 (1996-09-01), Goodley et al.
patent: 5747799 (1998-05-01), Franzen
patent: 5756994 (1998-05-01), Bajic
patent: 5965884 (1999-10-01), Laiko et al.
patent: 6060705 (2000-05-01), Whitehouse et al.
patent: 6124675 (2000-09-01), Bertrand et al.
patent: 6207954 (2001-03-01), Andrien et al.
patent: 6239428 (2001-05-01), Kunz
patent: 6534765 (2003-03-01), Robb et al.
patent: 6610986 (2003-08-01), Hartley
patent: 6750449 (2004-06-01), Marcus
patent: 6852969 (2005-02-01), Marcus et al.
patent: 6888132 (2005-05-01), Sheehan et al.
patent: 2005/0056775 (2005-03-01), Cody et al.
patent: 2005/0196871 (2005-09-01), Cody et al.
patent: 4215329 (1992-08-01), None
patent: 10088798 (1998-04-01), None
patent: WO-01/33605 (1999-10-01), None
patent: WO-01/33605 (1999-10-01), None
patent: WO-99/63576 (1999-12-01), None
patent: WO-00/08455 (2000-02-01), None
patent: WO-00/08456 (2000-02-01), None
patent: WO-00/08457 (2000-02-01), None
patent: WO 2004/098743 (2004-11-01), None
Hartley, F.T. et al., “NBC detection in air and water,” Micro/Nano 8, pp. 1, 2, and 8 (Dec. 2003).
Potjewyd, J., “Focusing of ions in atmospheric pressure gases using electrostatic fields,” Ph.D. Thesis, University of Toronto (1983).
Cody,R.B., et al., “Versatile new ion source for the analysis of materials in open air under ambient conditions”, Anal Chem 77, pp. 2297-2302 (2005).
McEwen, C.N., et al., “Analysis of solids, liquids, and biological tissues using solids probe introduction at atmospheric pressure . . . ”, Anal Chem 77, pp. 7826-7831 (2005).

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