Remedy for pemphigoid

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Reexamination Certificate

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C514S002600

Reexamination Certificate

active

07449177

ABSTRACT:
An agent for treatment of pemphigoid is provided.For use as an agent for treatment of pemphigoid, IFN-γ is administered in a dose of 2,000,000 JRU once daily for 7 days by intravenous drip infusion. Depending on symptoms, side effects and age of a patient, the dose can be change, or the dosage can changed to intravenous drip infusion given once in several days. IFN-γ is fast-acting against pemphigoid, involves few side effects, and is considered to be effective. The mechanism of action is presumed to be that IFN-γ suppresses the chemotaxis and function of eosinophils which are considered to be directly involved in the occurrence of pemphigoid.

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Fitzgerald, K.A., et al. The Cytokine Facts Book. 2001. Academic Press. 2nd Ed. p. 322-327.
International Search Report for PCT/JP03/17031 mailed Feb. 10, 2004 (PCT/ISA/210).
Physician's Desk Reference (2003), pp. 1756-1758.

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