Drug – bio-affecting and body treating compositions – Lymphokine – Interferon
Reexamination Certificate
2003-12-26
2008-11-11
Landsman, Robert (Department: 1646)
Drug, bio-affecting and body treating compositions
Lymphokine
Interferon
C514S002600
Reexamination Certificate
active
07449177
ABSTRACT:
An agent for treatment of pemphigoid is provided.For use as an agent for treatment of pemphigoid, IFN-γ is administered in a dose of 2,000,000 JRU once daily for 7 days by intravenous drip infusion. Depending on symptoms, side effects and age of a patient, the dose can be change, or the dosage can changed to intravenous drip infusion given once in several days. IFN-γ is fast-acting against pemphigoid, involves few side effects, and is considered to be effective. The mechanism of action is presumed to be that IFN-γ suppresses the chemotaxis and function of eosinophils which are considered to be directly involved in the occurrence of pemphigoid.
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Asubio Pharma Co. Ltd.
Hissong Bruce D.
Hunton & Williams LLP
Landsman Robert
Maruho Co. Ltd.
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