Remedies for hyperammonemia

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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Details

C514S054000, C514S025000, C536S004100, C536S123100, C536S123130, C363S021030, C399S301000, C424S093450, C600S322000, C435S253100

Reexamination Certificate

active

06852707

ABSTRACT:
By using xylobiose or xylooligosaccharide containing xylobiose as a main ingredient in place of lactulose, there is provided a blood ammonia lowering agent, a therapeutic agent of hyperammonemia or a therapeutic agent of hepatic encephalopathy that need be adminstered in smaller doses and which have no concern over side effects.Lactulose conventionally used as such drugs has to be administered in high doses and involves a safety problem when administered to patients with galactosemia or diabetes mellitus. The drug of the invention which contains xylobiose as a main ingredient solves these problems.

REFERENCES:
patent: 5939309 (1999-08-01), Suwa et al.
patent: 0265970 (1988-05-01), None
patent: 382355 (1990-08-01), None
patent: 382355 (1990-08-01), None
patent: 0459462 (1991-12-01), None
patent: 57-4922 (1982-01-01), None
Rikkers, “Portal hemodynamics, intestinal absorption, and postshunt encephalopathy.” Surgery, (Aug. 1983), 94(2), 126-133.*
Pai et al., “Treatment of porto-systemic encephalopathy with lactitol versus lactulose: a randomized controlled study.” Chung-Hua I Hsueh Tsa Chih (Chinese Medical Journal), (Jan. 1995), 55(1), 31-36.*
Mette Rye Clausen et al., “Lactulose, Disaccharides and Colonic Flora”, Drugs, vol. 53 No. 6 (Jun. 1997) pp930-942.
Delzenne N. et al., “Effect of Fermentable Fructo-Oligosacchardies On Mineral, Nitrogen and Energy Digestive Balance in the Rat”, Life Sciences, vol. 57, No. 17 (1995) pp 1579-1587.
Kajihara et al., “Effect of xylooligosaccharides on blood ammonia level” Hepatology, vol. 30, No. 4, part 2, Oct. 1999, p. 292A, XP001057358, Abstract.
Younes et al. “Fermentable Fibres or Oligosaccharides Reduce Urinary Nitrogen Excretion by Increasing Urea Disposal in the Rat Cecum” J. of Nutrition, vol. 125, No. 4 Apr. 1995 pp 1010-1016 XP001063206.

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