Remedies for dry eye and diseases associated with dry eye

Details Remedies for dry eye and diseases associated with dry eye Remedies for dry eye and diseases associated with dry eye

2002-11-05

2008-12-02

Tsang, Cecilia (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

Reexamination Certificate

active

07459441

ABSTRACT:
Remedies for dry eye and diseases associated with dry eye which contain as the active ingredient peptides represented by the general formula (I):in-line-formulae description="In-line Formulae" end="lead"?H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-X1-Gln-X2-Ala-Val-X3-X4-Tyr-Leu-X5-X6(SEQ ID NOS: 26-36)   (I)in-line-formulae description="In-line Formulae" end="tail"?wherein X1, X3and X4represent Lys or Arg, respectively; X2represents Met, Leu or nLeu; X5represents a chemical bond, Asn, Asn-Ser, Asn-Ser-Ile, Asn-Ser-Ile-Leu(SEQ ID NO: 37) or Asn-Ser-Ile-Leu-Asn-X7(SEQ ID NOS: 38-43) (wherein X7represents a chemical bond, Gly, etc.); and X6represents —OH or —NH2, or pharmaceutically acceptable salts thereof:.

REFERENCES:
patent: 4745100 (1988-05-01), Gilbard et al.
patent: 5856303 (1999-01-01), Kashimoto et al.
patent: 204447 (1986-12-01), None
patent: 796867 (1997-09-01), None
patent: 5-238950 (1993-09-01), None
patent: 2001-151799 (2001-06-01), None
Zoulikova et al. Synthesis of Fragments of the Vasoactive Intestinal Peptide (VIP) and Analysis of Their Residual Biological Activities. Collect. Czech. Chem. Commun., 1995, vol. 60, pp. 1229-1235.
http://www.anaspec.com/products/product.asp?id=31024 accessed online Dec. 21, 2007. p. 1 of 1.

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