Release tag compounds producing ketone signal groups

Details Release tag compounds producing ketone signal groups Release tag compounds producing ketone signal groups

1996-02-08

1997-03-11

Killos, Paul J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 72, 435 6, 435175, 435183, G01N 33566

Patent

active

056100205

ABSTRACT:
A release tag reagent suitable for use in the chemical analysis of a substance to be detected comprises signal, release, and reactivity groups. A class of release tag compounds that are cleaved to release as signal groups very stable electrophoric ketones which are sufficiently volatile for determination in the gas phase of an analytical reaction mixture is disclosed.

REFERENCES:
patent: 4629689 (1986-12-01), Diamond et al.
patent: 4650750 (1987-03-01), Giese
patent: 4709016 (1987-11-01), Giese
Buchet et al., "Le dosage par chromatographie en phase gaseuse des m etabolites urinaires du trichlor ethylene: l'acide trichloroac etique et le trichloro ethanol," Archives de Maladies Professionelles, de M edecine due Travial et de S ecurit e Sociale (Paris), 35:395-402 (1974).
Kawamatsu et al., Eur. J. Med. Chem.-Chim. Ther., 16(4) 355-362 [CA95(21): 187138c (1981)].
Landegren et al., "DNA Diagnostics--Molecular Techniques and Automation," Science 242:229-237 (1988).
Rotman, "Sequencing the entire human genome," Industrial Chemist, pp. 18-21, Dec. 1987.
Rudinger-Adler et al., "Arzneim.-Forsch.", 29(9) 1326-1331 [CA92(5):41712b (1979)].
Senft, "Simple determination of trichloroacetic acid in urine using head space gas chromatography: a suitable method for monitoring exposure to trichloroethylene," Journal of Chromatography 337:126-130 (1985).

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