Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1985-05-21
1987-02-10
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 14, 424 16, 424 19, 424 21, 424 22, 604890, 604892, A01N 2534, A61K 922, A61K 926
Patent
active
046422307
ABSTRACT:
A bolus for administering a biologically active material for example an insecticide into a liquid environment such as the water of a reservoir or lake or an anthelmintic into the rumen juices of an animal comprises a succession of liquid impermeable outer segments (153, 263) enclosing a core which in the simplest case may be a single unitary active material segment (151, FIG. 14) or in a developed embodiment may comprise a succession of annular segments (269, FIG. 25) contained in sealed recesses (267) in the outer segments (263) which are located on a degradable central rod (265) e.g. of magnesium alloy, which itself will be active for instance to combat magnesium deficiency.
As shown in FIG. 25, the device may incorporate a weight (275) which, in animal use, inhibits regurgitation. Additionally, the device may include a galvanic couple element which, with the rod (265) sets up a galvanic action which controls the speed of degradation of the rod (265) and thereby the rate of administration of the segments (26).
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Shepherd Michael T.
Whitehead Derek J.
Brown Donald
Castex Products Limited
Gammons Robert T.
Griffin Ronald W.
The Wellcome Foundation Limited
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