Relating to the detection of viruses

Details Relating to the detection of viruses Relating to the detection of viruses

1995-06-06

1999-03-16

Zitomer, Stephanie W.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530300, 530826, 530395, C07K 14045

Patent

active

058832254

ABSTRACT:
The present invention relates to polypeptides from clinical isolates of cytomegalovirus encoded by the gB coding region which include at least one amino acid variation which is a substitution, insertion or deletion wherein the polypeptides otherwise retain the character of cytomegalovirus. The amino acid variations include changes to neutralizing epitopes.

REFERENCES:
patent: 5547834 (1996-08-01), Spaete et al.
Cranage et al., The EMBO Journal 5(11):3057-3063 (1986).

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