Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2005-02-08
2005-02-08
Azpuru, Carlos A. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C424S486000, C428S116000
Reexamination Certificate
active
06852330
ABSTRACT:
A biocompatible tissue repair stimulating implant or “scaffold” device, and methods for making and using such a device, are provided. The implant includes one or more layers of a bioabsorbable polymeric foam having pores with an open cell pore structure. A reinforcement component is also present within the implant to contribute enhanced mechanical and handling properties. The implant houses a biological component that may be released to tissue adjacent the location in which the implant is implanted to faciliate and/or expedite the healing of tissue. This biological component resides primarily within the foam component of the implant, being incorporated within pores formed within the foam.
REFERENCES:
patent: 3812017 (1974-05-01), Santangelo et al.
patent: 3857932 (1974-12-01), Shepherd et al.
patent: 4520821 (1985-06-01), Schmidt et al.
patent: 4553272 (1985-11-01), Mears
patent: 4609551 (1986-09-01), Caplan et al.
patent: 4801299 (1989-01-01), Brendel et al.
patent: 4902508 (1990-02-01), Badylak et al.
patent: 5041138 (1991-08-01), Vacanti et al.
patent: 5053050 (1991-10-01), Itay
patent: 5061281 (1991-10-01), Mares et al.
patent: 5108989 (1992-04-01), Amento et al.
patent: 5147400 (1992-09-01), Kaplan et al.
patent: 5206023 (1993-04-01), Hunziker
patent: 5326357 (1994-07-01), Kandel
patent: 5425766 (1995-06-01), Bowald
patent: 5443950 (1995-08-01), Naughton et al.
patent: 5445833 (1995-08-01), Badylak et al.
patent: 5455041 (1995-10-01), Genco et al.
patent: 5480827 (1996-01-01), Guillemin et al.
patent: 5514181 (1996-05-01), Light et al.
patent: 5577517 (1996-11-01), Bonutti
patent: 5632745 (1997-05-01), Schwartz
patent: 5677355 (1997-10-01), Shalaby et al.
patent: 5681353 (1997-10-01), Li et al.
patent: 5709854 (1998-01-01), Griffith-Cima et al.
patent: 5720969 (1998-02-01), Gentile et al.
patent: 5723331 (1998-03-01), Tubo et al.
patent: 5736372 (1998-04-01), Vacanti et al.
patent: 5755791 (1998-05-01), Whitson et al.
patent: 5759190 (1998-06-01), Vibe-Hansen et al.
patent: 5766631 (1998-06-01), Arnold
patent: 5769899 (1998-06-01), Schwartz et al.
patent: 5786217 (1998-07-01), Tubo et al.
patent: 5830493 (1998-11-01), Yokota et al.
patent: 5837235 (1998-11-01), Mueller et al.
patent: 5842477 (1998-12-01), Naughton et al.
patent: 5891558 (1999-04-01), Bell et al.
patent: 5902741 (1999-05-01), Purchio et al.
patent: 5904716 (1999-05-01), Gendler
patent: 5904717 (1999-05-01), Brekke et al.
patent: 5914121 (1999-06-01), Robey et al.
patent: 5964805 (1999-10-01), Stone
patent: 5968096 (1999-10-01), Whitson et al.
patent: 5980889 (1999-11-01), Butler et al.
patent: 5989269 (1999-11-01), Vibe-Hansen et al.
patent: 5990194 (1999-11-01), Dunn et al.
patent: 5990378 (1999-11-01), Ellis
patent: 6001352 (1999-12-01), Boyan et al.
patent: 6001394 (1999-12-01), Daculsi et al.
patent: 6005161 (1999-12-01), Brekke et al.
patent: 6027742 (2000-02-01), Lee et al.
patent: 6080579 (2000-06-01), Hanley, Jr. et al.
patent: 6096532 (2000-08-01), Armstrong et al.
patent: 6103255 (2000-08-01), Levene et al.
patent: 6110209 (2000-08-01), Stone
patent: 6120514 (2000-09-01), Vibe-Hansen et al.
patent: 6121042 (2000-09-01), Peterson et al.
patent: 6123727 (2000-09-01), Vacanti et al.
patent: 6132463 (2000-10-01), Lee et al.
patent: 6139578 (2000-10-01), Lee et al.
patent: 6140039 (2000-10-01), Naughton et al.
patent: 6143293 (2000-11-01), Weiss et al.
patent: 6153292 (2000-11-01), Bell et al.
patent: 6179872 (2001-01-01), Bell et al.
patent: 6180007 (2001-01-01), Gentile et al.
patent: 6183737 (2001-02-01), Zaleske et al.
patent: 6187053 (2001-02-01), Minuth
patent: 6197061 (2001-03-01), Masuda et al.
patent: 6200606 (2001-03-01), Peterson et al.
patent: 6214045 (2001-04-01), Corbitt, Jr. et al.
patent: 6251673 (2001-06-01), Winkler
patent: 6277151 (2001-08-01), Lee et al.
patent: 6283980 (2001-09-01), Vibe-Hansen et al.
patent: 6287340 (2001-09-01), Altman et al.
patent: 6291240 (2001-09-01), Mansbridge et al.
patent: 6306424 (2001-10-01), Vyakarnam et al.
patent: 6319712 (2001-11-01), Meenen et al.
patent: 6331312 (2001-12-01), Lee et al.
patent: 6365149 (2002-04-01), Vyakarnam et al.
patent: 6379367 (2002-04-01), Vibe-Hansen et al.
patent: 6511958 (2003-01-01), Atkinson et al.
patent: 6541024 (2003-04-01), Kadiyala et al.
patent: 6599323 (2003-07-01), Melican et al.
patent: 6605294 (2003-08-01), Sawhney
patent: 20010016353 (2001-08-01), Janas et al.
patent: 20010023373 (2001-09-01), Plouhar et al.
patent: 20010039453 (2001-11-01), Gresser et al.
patent: 20010053353 (2001-12-01), Griffith et al.
patent: 20010053839 (2001-12-01), Noishiki et al.
patent: 20020009805 (2002-01-01), Nevo et al.
patent: 20020009806 (2002-01-01), Hicks, Jr.
patent: 20020029055 (2002-03-01), Bonutti
patent: 20020082631 (2002-06-01), Bonutti
patent: 20020091403 (2002-07-01), Bonutti
patent: 20020091406 (2002-07-01), Bonutti
patent: 20020099401 (2002-07-01), Bonutti
patent: 20020099448 (2002-07-01), Hiles et al.
patent: 20020107570 (2002-08-01), Sybert et al.
patent: 20020127265 (2002-09-01), Bowman et al.
patent: 20020133229 (2002-09-01), Laurencin et al.
patent: 20030026787 (2003-02-01), Feamot et al.
patent: 20030077311 (2003-04-01), Vyakarnam et al.
patent: 19812195 (1999-09-01), None
patent: 0955024 (1910-04-01), None
patent: 0274898 (1987-12-01), None
patent: 0 562 864 (1993-09-01), None
patent: 0562864 (1993-09-01), None
patent: 0 955 024 (1999-11-01), None
patent: 1064958 (2001-01-01), None
patent: 1 064 958 (2001-01-01), None
patent: 1 167 517 (2002-01-01), None
patent: WO 8600533 (1986-01-01), None
patent: WO 9533821 (1995-12-01), None
patent: WO 9730662 (1997-08-01), None
patent: WO 9746665 (1997-12-01), None
patent: WO 9848860 (1998-11-01), None
patent: 0016381 (1999-04-01), None
patent: WO 9947097 (1999-09-01), None
Stone, K. et al. “Meniscal Regeneration With Copolymeric Collagen Scaffolds” American Journal of Sports Medicine, 20(2):104-111 (1992).
Murray, M., et al. “The Migration of Cells from the Ruptured Human Anterior Cruciate Ligament into Collagen-Glycosaminoglycan Regeneration Templated in Vitro” Biomaterials 22:2393-2402 (2001).
*(Abstract Only) Caterson EJ., et al. “Three-Dimensional Cartilage Formation by Bone Marrow-Derived Cells Seeded in Polylactide/Alginate Amalgam” J Biomed Mater Res, 57(3):394-403 (2001).
*(Abstract Only) Grigolo, B., et al. “Transplantation of Chondrocytes Seeded on a Hyaluronan Derivative (hyaff-11) into Cartilage Defects in Rabbits” Biomaterials 22(17):2417-2424 (2001).
*(Abstract Only) van Susante JLC, et al. “Linkage of Chondroitin-sulfate to Type I Collagen Scaffolds Stimulates the Bioactivity of Seeded Chondrocytes in Vitro”, Biomaterials, 22(17):2359-2369 (2001).
*(Abstract Only) Hutmacher DW., “Scaffold Design and Fabrication Technologies for Engineering Tissues-State of the Art and future Prospectives”, J Biomater Sci Polym Ed, 12(1):107-124 (2001).
*(Abstract Only) Hutmacher DW., “Scaffolds in Tissue Engineering Bone and Cartilage”, Biomaterials, 21(24):2529-2543 (2000).
*(Abstract Only) Schreiber RE., et al. “A Method for Tissue Engineering of cartilage by Cell Seeding on Bioresorbable Scaffolds” Ann NY Acad Sci, 875:394-404 (1999).
*(Abstract Only) Radice, M. “Hyaluronan-Based Biopolymers as delivery vehicles for Bone-Marrow-Derived Mesenchymal Progenitors”, J Biomed Mater Res, 50(2):101-9 (2000).
Albrecht, F., “Closure of Osteochondral Lesions Using Chondral Fragments and Fibrin Adhesive” Arch. Orthop. Trauma Surg. (1983) 101:213-217.
Thomas F. Deuel and Nan Zhang, “Growth Factors” in Principles of Tissue Engineering, Second Edition, Academic Press, 2000, pp. 129-141.
Sally R. Frenkel, Ph.D. and Paul E. Di Cesare, M.D., “Degradation and Repair of Articular Cartilage” in Frontiers in Bioscience, 4thed ., pp. 671-685, Oct. 15, 1999, pp. 1-32.
Keith J. Gooch et al., “Mechanical Forces and Growth Factors Utilized in Tissue Engineering” in Frontier in Tissue Engineering, Perg
Bowman Steven M.
Bruker Izi
Rezania Alireza
Azpuru Carlos A.
DePuy Mitek, Inc.
McClennen & Fish LLP
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