Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-11-14
2006-11-14
Andres, Janet L. (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C514S04400A, C530S350000, C536S023500
Reexamination Certificate
active
07135303
ABSTRACT:
The present invention provides compositions and methods for the regulation of cytokine signaling through the Tumor Necrosis Factor (TNF) pathway. Specifically, the invention provides a novel gene, polypeptide and related compositions and methods for the regulation of ectodomain shedding. In preferred embodiments, methods and compositions for the regulation of TNF Type-1 Receptor ectodomain shedding are provided. The present invention finds use in therapeutics, diagnostics, and drug screening applications.
REFERENCES:
patent: 5972680 (1999-10-01), Knowles et al.
patent: 12 48 204 (1967-08-01), None
patent: 0 657 536 (1995-06-01), None
patent: WO 98 20140 (1998-05-01), None
patent: WO 99 58559 (1999-11-01), None
patent: WO 99 63088 (1999-12-01), None
patent: WO 00 32221 (2000-06-01), None
patent: WO 00 73454 (2000-12-01), None
patent: WO 00 75375 (2000-12-01), None
Fitzgerald et al. The Cytokines Facts Book (2ndedition); San Diego: Academic Press, 2001, pp. 21-28.
Thomas (Ed). Tabers Cyclopedic Medical Dictionary (15thedition); Philadelphia: F.A. Davis Company, 1985, p. 870.
Cui et al., Database' Em—Hum [Online] EBML; Feb. 16, 2000, Accession No. AF222340.
Garcia-Alvarez et al.,Eur. J. Biochem., 202, 993-1002 (1991).
Hattori et al.,J. Biochem., 125(5), 931-938 (1999).
Hirokawa et al.,Bioinform., 14(4), 378-379 (1998).
Hofmann et al.,Biol. Chem. Hoppe-Seyler 374, 166 (1993).
Keller et al.,J. Biol. Chem., 270(40), 23612-23618 (1995).
Kyte et al.,J. Mol. Biol., 157, 105-132 (1982).
Levine et al.,Am. J. Respir.Cell Mol. Biol., 12(2), 196-204 (1995).
Li et al.,Genomics, 17, 657-664 (1993).
McGuffin et al.,Bioinform., 16(4), 404-405 (2000).
Nanus et al.,Proc. Natl. Acad. Sci, USA, 90, 7069-7073 (1993).
Olsen et al.,FEBS Lett., 238(2), 307-314 (1988).
Persson et al.,J. Mol. Biol. 237, 182-192 (1994).
Rogi et al.,J. Biol. Chem, 271(1), 56-61 (1996).
Schauder et al.,Proc. Natl. Acad. Sci. USA, 91, 9534-9538 (1994).
Tan et al.,FEBS Lett., 306(1), 9-16 (1992).
Tobler et al.,J. Neurochem, 68(3), 889-897 (1997).
von Heijne,J. Mol. Biol., 225, 487-494 (1992).
Wilson et al.,Nature, 368, 32-38 (1994).
Zinc Metalloproteases in Health and Disease, Taylor & Francis, London, England (1996), Hooper, p. 1-21, and Wang and Cooper, p. 131-151.
Andres Janet L.
Emch Gregory S
Leydig Voit & Mayer Ltd
The United States of America as represented by the Department of
LandOfFree
Regulators of type-1 tumor necrosis factor receptor and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Regulators of type-1 tumor necrosis factor receptor and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Regulators of type-1 tumor necrosis factor receptor and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3656002