Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Reexamination Certificate
2006-08-29
2006-08-29
Lewis, Patrick (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
C514S075000, C514S079000, C514S080000, C435S004000, C436S071000, C530S300000, C530S350000
Reexamination Certificate
active
07098196
ABSTRACT:
The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function mutations.
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Beachy Philip A.
Chen James K.
Taipale Anssi J.
Johns Hopkins University School of Medicine
Lewis Patrick
LandOfFree
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