Regulation of translation for recombinant protein production

Details Regulation of translation for recombinant protein production Regulation of translation for recombinant protein production

2006-08-15

2006-08-15

Vogel, Nancy (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S325000, C435S358000, C435S359000, C435S360000, C435S361000, C435S455000

Reexamination Certificate

active

07091004

ABSTRACT:
The invention provides cells that produce increased levels of recombinant protein by modulating the activity of translational regulator gene products that are downstream targets of PKB alpha, methods of making such cells, and methods of using such cells. Such translational regulator gene products include 4E-BP1 and mTOR.

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