Regulation of transcription factor, NF-IL6/LAP

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435 72, 435194, C12Q 148, G01N 3350, C12N 912

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active

058742093

ABSTRACT:
An alteration in phosphorylation of serine 105, within the activation domain of NF-IL6/LAP, alters its transcriptional efficacy. Polypeptides, polynucleotides and methods of use for modified transcriptional activators allow regulation of gene expression.

REFERENCES:
Chang, et al., Molecular and Cellular Biology, Molecular Cloning of a Transcription Factor, AGP/EBP, That Belongs to Members of the C/EBP Family, 10, 12:6642-6653, 1990.
Ron et al. Genes and Development vol. 6(3): pp. 439-453 (1992).

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