Regulation of plant fertility by modulation of GABA levels...

Plant protecting and regulating compositions – Plant growth regulating compositions – Organic active compound containing

Reexamination Certificate

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C504S271000, C504S275000, C504S292000, C504S320000, C504S322000, C504S326000

Reexamination Certificate

active

07109149

ABSTRACT:
The invention provides methods for the alteration of fertility in plants through modulation of floral GABA levels. The techniques of the invention may find use in plant breeding techniques. Also provided by the invention are assays for the screening of candidate modulators of GABA metabolism or GABA analogs through the identification of affects on fertility following application of the candidate modulator to a plant. The technique provides an alternative to animal testing and is amenable to large scale application.

REFERENCES:
patent: 4936904 (1990-06-01), Carlson
patent: 5439873 (1995-08-01), Kinnersley
patent: 6075051 (2000-06-01), Cohen
patent: 6268206 (2001-07-01), Liptak
patent: 6534446 (2003-03-01), Kinnersley et al.
patent: WO 00/61763 (2000-10-01), None
Narayan et al. “Metabolism, enzymology and possible roles of 4-aminobutyrate in higher plants”, Review Article No. 51, Phytochemistry. 29(2):367-375. 1990.
Bown et al. “TheMetabolism and Functions of γ-Aminobutyric Acid” Update on Biochemistry. Plant Physiology. 115:1-5. 1997.
Devlin, “The pharmacology of γ-aminobutyric acid and acetylcholine receptors at the echinoderm neuromuscular junction,”J Exp Biol., 204(Pt 5):887-896, 2001.
Enna, “Gaba receptor pharmacology. Functional considerations,”Biochem. Pharmacol., 30:907-915, 1981.
GenBank Accession No. AF351125.
Jefferson, “Benzodiazepines and anticonvulsants for social phobia (social anxiety disorder),”J Clin Psychiatry., 62 Suppl 1:50-53, 2001.
Krysan et al., “T-DNA as an insertional mutagen in Arabidopsis,”Plant Cell, 11(12):2283-2290, 1999.
Potschka et al., “Gabapentin-lactam, a close analogue of the anticonvulsant gabapentin, exerts convulsant activity in amygdala kindled rats,”Naunyn Schmiedebergs Arch Pharmacol., 361(2):200-205., 2000.
Schousboe, “Pharmacological and functional characterization of Astrocytic GABA transport: a short review,”Neurochem Res., 25(9-10):1241-1244, 2000.
Schwartz, “The GabaAreceptor-gated ion channel: biochemical and pharmacological studies of the structure and function,”Biochem. Pharmacol., 27:3369-3376, 1988.
Shelp et al., “Metabolism and function of gamma-aminobutyric acid,”Trends Plant Sci., 4(11):446-452, 1999.
Wilhelmi and Preuss, “Self-sterility in Arabidopsis due to defective pollen tube guidance,”Science., 274(5292):1535-1537, 1996.
Wilhelmi,In: The Arabidopsis POP2 and POP3 Genes: Key Components in Pollen Tube Guidance, Ph.D. thesis, The University of Chicago, 1999.
Database EMBL., May 15, 2001, Database accession No. AF351125.
Database GSP, Mar. 6, 2001, Database accession No. AAB19490.
Mascarenhas, Joseph P. “Molecular mechanisms of pollen tube growth and differentiation,”Plant Cellvol. 5, No. 10, 1993, pp. 1303-1314.
Palanivelu, Ravishankar et al. “Pollen tube targeting and axon guidance: Parallels in tip growth mechanisms,”Trends in Cell Biology, Vo. 10, No. 12, Dec. 2000, pp. 517-524.

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