Regulation of intracellular glucocorticoid concentrations

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase

Reexamination Certificate

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C435S004000

Reexamination Certificate

active

06838253

ABSTRACT:
Therefore, another aspect of the invention is a method for determining whether a compound or composition is a regulator of intracellular glucocorticoid activity in adipose tissue comprising determining whether said compound or composition inhibits reductase activity of 11-Beta-hydroxysteroid dehydrogenase 1 (11-Beta HSD1) in said tissue.

REFERENCES:
patent: 6368816 (2002-04-01), Walker et al.

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