Regulation of immune response

Details Regulation of immune response Regulation of immune response

1994-10-20

1996-09-24

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

514182, A61K 3156

Patent

active

055591078

ABSTRACT:
Androsta-5,7-diene-3.beta.,17.beta.-diol, its esters and ethers and related compounds wherein ring opening of the steroid ring system between carbons 9 and 10 has occurred are active as regulators of immune response and cell proliferation and differentiation.

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patent: 5407684 (1995-04-01), Loria et al.
Chemical Abstracts, vol. 106, No. 19 issued 18 May 1987, Kubodera et al., "9,10-Secoandrostane (vitamin D) compounds", see page 720, column 2, abstract No. 156775z, Jpn Kokai Tokkyo Koho Jp 61,267,551.
Chemical Abstracts, vol. 117, No. 21 issued 01 Dec. 1992, Sicinski, "Photochemical and thermal isomerizations of 19 functionalized previtamin D analogs in the androstane series", see p. 877, column 1, abstract No. 212780p, Acta Chim. Hung., 129(2), 191-200.
Butenandt, et al., Berichte, 71, 1316-22 (1938).
Milas et al., J. Am. Chem. Soc., 68, 738-40 (1946).

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