Regulation of human wee1-like serine/threonine protein kinase

Details Regulation of human wee1-like serine/threonine protein kinase Regulation of human wee1-like serine/threonine protein kinase

2006-05-30

2006-05-30

Monshipouri, Maryam (Department: 1653)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C536S023200, C530S350000

Reexamination Certificate

active

07052892

ABSTRACT:
Reagents that regulate human WEE1-like serine/threonine protein kinase and reagents which bind to human WEE1-like serine/threonine protein kinase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, peripheral and central nervous system disorders, genitourinary disorders, cardiovascular disorders, and COPD.

REFERENCES:
Watanabe et al.(1995) Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle.EMBO J 1;14(9):1878-91.
McGowan and Russell (1995) Cell cycle regulation of human WEE1. EMBO J 14(10):2166-75.
Hanks and Hunter (1995) Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain stucture and classification. FASEB J 9(8):576-96.
Du H. et al. Database EMBL ‘Online’ “The sequence of Homo sapiens PAC clone RP5-894a 10” Database accession No. 095017.
Bagguley C. Database EMBL ‘Online’ “Human DNA sequence from clone RP5-916011” Database accession No. AL136146.10
Mueller Paul R et al: “Cell cycle regulation of a Xenopus Weel-like kinase.” Molecular Biology of the Cell, vol. 6, No. 1, 1995, pp. 119-134.
Tiranti Valeria et al: “Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB).” Gene (Amsterdam), vol. 126, No. 2, 1993, pp. 219-225.

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