Regulation of human transketolase-like enzyme

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

Reexamination Certificate

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C435S193000, C536S023200

Reexamination Certificate

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06919185

ABSTRACT:
Reagents which regulate human transketolase-like enzyme and reagents which bind to human transketolase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, anemia, and end-stage renal disease, including sensory periphery neuropathy associated with uremia.

REFERENCES:
patent: WO 97/05253 (1997-02-01), None
patent: WO 01/12659 (2001-02-01), None
patent: WO 01/66752 (2001-09-01), None
A_GeneSeq Data Base Acc#ABU52999 WO200112659 PD Feb. 22, 2001 Wiemann S. Alignment with SEQ ID NO: 2.
Database EMBL ′Online!, “SEQ ID NO: 513 from patent WO 01 12659”, Feb. 22, 2001, Database Accession No. AX086561, XP002185367.
Database EMBL ′Online!, “SEQ ID NO: 512 from patent WO 01 12659”, Mar. 6, 2001, Database Accession No. AX086560, XP002185368.
Database EMBL ′Online!, “SEQ ID NO: 511 from patent WO 01 12659”, Mar. 9, 2001, Database Accession No. AX086559, XP002184772.
Database EMBL ′Online!, Mar. 3, 2000, retrieved from EBI Database Accession No. AC015457, XP002184732,Homo sapienschromosome 4, clone RP11-218F10, Nucleotides: 38520-42060.
Database EMBL ′Online!, “H. sapiensmRNA for transketolase-like protein”, Database Accession No. X91817, XP002185233 (Mar. 1996).
Coy J. F., et al., “Molecular Cloning of Tissue-Specific Transcripts of a Transketolase-Related Gene: Implications for the Evolution of New Vertebrate enes”, Genomics, Academic Press, San Diego, US, Mar. 15, 1996, vol. 32, No. 3, pp 309-316, XP000616489.
McCool B. A., et al., “Cloning of Human Transketolase CDNAS and Comparison of the Nucleotide Sequence of the Coding Region in Wernicke-Korsakoff and Non-Wernicke-Korsakoff Individuals”, Journal Of Biological Chemistry, American Society of Biological Chemists, Baltimore, MD, Jan. 15, 1993, vol. 268, No. 2, pp 1397-1404, XP002023965.

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