Regulation of human protein phosphatase IIc-like enzyme

Details Regulation of human protein phosphatase IIc-like enzyme Regulation of human protein phosphatase IIc-like enzyme

2006-06-13

2006-06-13

Slobodyansky, Elizabeth (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

C435S196000

Reexamination Certificate

active

07060456

ABSTRACT:
Reagents which regulate human protein phosphatase IIC-like enzyme-like enzyme activity and reagents which bind to human protein phosphatase IIC-like enzyme-like enzyme gene products can be used, inter alia, to treat disorders associated with an increase in apoptosis, including AIDS and other infectious or genetic immunodeficiencies, neurodegenerative diseases, myelodysplasia, ischemic injuries, toxin-induced diseases, wasting diseases, viral infections, and osteoporosis. Regulation of human protein phosphatase IIC-like enzyme-like enzyme also can be used to treat disorders associated with a decrease in apoptosis, including cancer, diabetes, CNS disorders, cardiovascular disorders, chronic obstructive pulmonary diseases, and inflammatory disorders also can be treated.

REFERENCES:
patent: WO 99 38972 (1999-08-01), None
patent: WO 99 58675 (1999-11-01), None
patent: WO 02 18424 (2002-03-01), None
Kashiwaba et al (2003) FEBS Letters, vol. 538, pp. 197-202.
Database EMBL “Online” Dec. 16, 1999 Database accession No. AL133644 (XP002207991).
Database EMBL “Online” May 1, 2000 Database accession No. Q9UF84 (XP002208006).
Database EMBL “Online” May 19, 2000 Database accession No. AAA02311 (XP002207992).
Database EMBL “Online” Oct. 12, 1999 Database accession No. AAZ12841 (XP002207993).
Database EMBL “Online” Oct. 21, 1999 Database accession No. AW117553 (XP002208045).
Database EMBL “Online” Jun. 19, 1998 Database accession No. AI024671 (XP002208046).
Database EMBL “Online” Oct. 6, 1998 Database accession No. AI167220 (XP002208047).
Database EMBL “Online” Aug. 3, 2001 Database accession No. BC011803 (XP002207994).
Database EMBL “Online” Feb. 8, 2001 Database accession No. AK009235 (XP002207995).
Database EMBL “Online” Jun. 6, 2002 Database accession No. AX400071 (XP002208000).
Barford, D: “Molecular mechanisms of the protein serine/threonine phosphatases”, TIBS Trends in Biochemical Sciences Elsevier Publication, vol. 21, No. 11, Nov. 1, 1996, pp. 407-412 , XP004071015.
Price, N.E. and Mumby, M.C.: “Brain protein serine/threonine phosphates”, Current Opinion in Neurobiology, vol. 9, 1999, pp. 336-342, XP002207990.
Tong, Y et al.: “Cloning and characterization of a Novel Mammalian PP2C Isozyme”, The Journal of Biological Chemistry, vol. 273, No. 52, Dec. 25, 1998, pp. 35282-35290.
Kusuda, K. et al.: Mutational analysis of the domain structure of mouse protein phosphatase 2Cβ, Biochem J., (1998) 332, pp. 243-250.

Affiliated with

Also associated with

Rating

Regulation of human protein phosphatase IIc-like enzyme does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Regulation of human protein phosphatase IIc-like enzyme, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Regulation of human protein phosphatase IIc-like enzyme will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3652245