Regulation of human ceramide kinase

Details Regulation of human ceramide kinase Regulation of human ceramide kinase

2006-05-02

2006-05-02

Monshipouri, Maryam (Department: 1653)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C530S350000, C435S252300, C435S320100, C435S006120

Reexamination Certificate

active

07037700

ABSTRACT:
Reagents that regulate human ceramide kinase protein activity and reagents that bind to human ceramide kinase gene products can be used to regulate intracellular signaling and consequently cell proliferation and apoptosis. Such regulation is particularly useful for treating allergies including but not limited to asthma, autoimmune diseases such as rheumatoid arthritis, inflammatory disease, transplant rejection, and cancer, particularly lymphocytic leukemias, and could be a useful target of vaccination enhancing adjuvants. Central and peripheral nervous system disorders, such as Parkinson's disease, also can be treated.

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ABSTRACT, Database EMBL 'Online, Bates K: Database accession No. Q9UGE5, XP002208103, May, 1, 2000.

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