Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-04-14
1998-07-07
LeGuyader, John L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 435325, 536 231, 536 235, C12P 2106, C12N 1500, C12N 500, C07H 2102
Patent
active
057766983
ABSTRACT:
The present invention provides a human regulator of gene transcription (HRGT) and polynucleotides which encode HRGT. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HRGT.
REFERENCES:
Hillier et al. Genbank. Accession #Z84468. Jan. 22, 1997.
Katzav, S., et al., "Loss of the Amino-Terminal Helix-Loop-Helix Domain of the vav Proto-Oncogene Activates Its Transforming Potential," Molecular and Cellular Biology, 11(4):1912-1920 (1991).
Benezra, R., et al., "The Protein Id: A Negative Regulator of Helix-Loop-Helix DNA Binding Proteins," Cell, 61:49-59 (1990) (GI 202344; GI 202343; GI 340190).
Goli Surya K.
Hillman Jennifer L.
Streeter David G.
Billings Lucy J.
Incyte Pharmaceuticals Inc.
LeGuyader John L.
Wang Andrew
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