Regulation of gene expression using chromatin remodelling...

Details Regulation of gene expression using chromatin remodelling... Regulation of gene expression using chromatin remodelling...

2005-02-22

2009-06-30

Worley, Cathy Kingdon (Department: 1638)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

Introduction of a polynucleotide molecule into or...

C435S455000, C435S471000, C435S440000, C800S278000, C536S023400, C536S024100, C536S023600

Reexamination Certificate

active

07553667

ABSTRACT:
The invention provides a method to regulate expression of a gene of interest in a plant comprising, introducing into the plant a first nucleotide sequence comprising, the gene of interest operatively linked to a first regulatory region, and an operator sequence capable of binding a fusion protein, and a second nucleotide sequence comprising a second regulatory region in operative association with a nucleotide sequence encoding the fusion protein. The fusion protein comprising, a DNA binding protein, or a portion thereof, capable of binding the operator sequence, and a recruitment factor protein, or a portion thereof, capable of binding a chromatin remodelling protein. In this manner, expression of the second nucleotide sequence produces the fusion protein that regulates expression of the gene of interest.

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