Regulation of eucaryotic gene expression

Details Regulation of eucaryotic gene expression Regulation of eucaryotic gene expression

1985-12-12

1989-05-23

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

438 68, 438 91, 438235, 4383171, 438320, 438255, 536 27, 931 29, 931 32, 931 33, 931 34, 931 56, 931 69, C12N 1500, C12N 2100, C12N 700, C12P 1934

Patent

active

048330809

ABSTRACT:
Regulation of eucaryotic gene expression is controlled by procaryotic peptides. The peptides recognize specific DNA sequences present in the gene, which may be derived from procaryotic genes, and either activate or repress gene transcription. Hybrid procaryotic peptides may be used containing both repressor and activator peptides.

REFERENCES:
Wharton et al., (1984) Cell 38: 361-369.
Echols pp. 252-262 in The Bacteriophage Lambda, ed. Hershey, Cold Spring Harbor Labs, New York, 1971.
Guarente et al. (1982) PNAS 79: 1410.
Sinclair et al., J. Mol. Cell. Biol., vol. 5, p. 3208 (1985).
Guarente et al., Cell, vol. 36, p. 799 (1984).
Guarente et al., Proc. Natl. Acad. Sci. U.S., vol. 79, p. 7410 (1982).
West et al., Molec. Cell Biol., vol. 4, p. 2467 (1984).
Brent et al., Nature, vol. 312, pp. 612-615 (1984).
Brent et al., Cell, vol. 43(2), pp. 729-736 (Dec. 1985).

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