Regulation of cytokine production in a hematopoietic cell

Details Regulation of cytokine production in a hematopoietic cell Regulation of cytokine production in a hematopoietic cell

1996-05-31

1999-06-08

Ulm, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 436501, 514 2, G01N 3353, A01N 3718

Patent

active

059104171

ABSTRACT:
A method useful for regulating cytokine production by a hematopoietic cell by regulating an MEKK/JNKK-contingent signal transduction pathway in such a cell is disclosed. Methods of identifying compounds capable of specifically regulating an MEKK/JNKK-contingent signal transduction pathway in hematopoietic cells, a kit for identifying cytokine regulators, methods to treat diseases involving cytokine production, and cells useful in such methods are also set forth.

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